Drug nanocrystals are a formulation principle for systemic and also, intracellular delivery of poorly soluble drugs. Their production by bottom-up techniques (precipitation – hydrosols,Nanomorph) and by top-down techniques (bead milling –NanoCrystal®, high pressure homogenization – DissoCubes®, NANOEDGE®) is briefly described, representing the first generation of nanocrystals. The second generation, the smart- Crystal®, is produced by combination processes. They are featured by e.g., increased physical stability and/or smaller sizes (< 100 nm), favorable when exposed to the destabilizing electrolytes in biological fluids and for uptake by cells by pinocytosis. The lab scale processes were successfully transferred to industrial scale by using discontinuous bead mills and high-capacity homogenizers (top down), precipitation can be performed by static blenders. According to the nanotoxico2 logical classification system (NCS), the nanocrystals belong to class I, being highly tolerable. They can be produced using only regulatorily accepted excipients. Both ease the way to the patient and market. Nanotoxicity studies confirm the good tolerability.
German Innovation Award
Dr. Ranjita Shegokar, CSO was honored with a German Innovation Award 2022 jointly with Prof. Marc A. Reymond, MD MBA (AACSB), CEO, CapnoPharm GmbH, for their collaborative, innovative research work in the field of cancer. https://www.german-innovation-award.de/en/winners/preis/gewinner/capnopen-capnodrugs/
German medical device firm races to provide alternative treatments to treat cancer
Revolutionizing Cancer Treatment
Hon’ble Ministers of State Shri Ashok Chandra Panda, Science & Technology, Public Enterprises, Social Security & Empowerment of Persons with Disability inaugurated the event in the auspicious presence of Padma Vibhusan Pandit Hariprasad Chaurasia and Padmashri Pt. Bhajan Sapori 15 women achievers in distinct categories felicitated with the prestigious award Parichay Foundation presents… Continue reading AARYA Award
International Inspirational Women Awards 2020
16 Best New Drug Delivery Systems Books To Read In 2021 – BookAuthority